Lets hear about that game you love, yet naggs at you with some unresolved plot element.
My choice is BioShock.
I love the game and back story, but one thing has allways bugged me about it.
SPOILER!!!!!!!
Don't read if you haven't played the game and don't want any plot ruined.
Why isn't Andrew Ryan revived by a vita chamber??
Its explained in the game that the vita chamber can revive people and that Ryan had it set to only work for him. As his son it will work for you due to the security not being perfected.
Unless that is a plot element in the sequel.